CURRENT RESEARCH STUDIES
If you are interested in participating in a research study, please send
an email to research@ranchoresearch.org with the following information:
Full Name:
Contact Number:
Email Address:
Briefly explain your motivation to participate:
Alternatively, you can call our office at (562) 385-8111 during regular business hours to
express your interest and provide the necessary details over the phone.
Indication:
Adverse childhood experiences
Title:
Virtual Meditation as a Response to Adverse Childhood Events
Description:
Study would like to identify the potential benefits of virtual meditation among pediatric patients with a history of adverse childhood experiences (ACEs). Meditation sessions will be delivered virtually to reach a broad patient population and encourage participation. Six sessions will be delivered weekly, each lasting for an hour. Age range will be 11 to 20 years old. Aside from the meditations, participants will also complete questionnaires and interviews at different time points.
Investigator:
Laura Figueroa-Phillips, MD
Sponsor:
Funding:
Indication:
Cardiac Rehabilitation
Title:
Cardiac Rehab Quality Improvement Study
Description:
Study would like to examine and intervene on the barriers to Cardiac Rehabilitation (CR), from both the physician and the patient perspective, by exploring ways to increase CR referrals, enrollment, and utilization. Potential subjects will be adults requiring CR due to recent MI, percutaneous coronary stenting, heart valve repair/ replacement, stable angina, congestive heart failure, heart transplant, or coronary artery bypass surgery. Research procedures include survey administration and review of patient records.
Investigator:
Grace Chen, MD
Sponsor:
Funding:
Indication:
Chopart amputation
Title:
Retrospective review of Chopart's Amputation With Double Tendon Transfers for High Risk Limb Salvage at a Single Center
Description:
Review of records and surgical technique of patients who underwent Chopart amputation since 11/21/2019 to evaluate outcomes and propose a new tendon transfer approach to be performed alongside the “classic” Chopart’s disarticulation.
Investigator:
Tanzim Khan, DPM
Sponsor:
Funding:
Indication:
Chronic kidney disease
Title:
GKPTN
Description:
A Prospective International Multi-Centre, Observational Cohort Study of Incident and Prevalent Patients Diagnosed with a Kidney Disease
Investigator:
Nina Patel, MD
Sponsor:
The George Clinical Institute for Global Health
Funding:
Industry
Indication:
Chronic kidney disease
Title:
ZENITH
Description:
A Phase 2b Multicentre, Randomised, Double-Blind, Placebo- Controlled, Parallel Group Dose-Ranging Study to Assess the Efficacy, Safety and Tolerability of Zibotentan and Dapagliflozin in Patients with Chronic Kidney Disease with an eGFF Between 20 and 60 mL/min/1.73 m2
Investigator:
Nina Patel, MD
Sponsor:
AstraZeneca
Funding:
Industry
Indication:
Chronic urinary retention
Title:
FREEDOM
Description:
Evaluation of the Safety and Clinical Performance of the Gen 2 Connected Catheter – Wireless Urinary Prosthesis for Management of Chronic Urinary Retention
Investigator:
Evgeniy Kreydin, MD
Sponsor:
UroDev
Funding:
Indication:
Dementia
Title:
Improving Support for Latino Caregivers of Persons with Early Onset Dementia
Description:
Study would like to develop tools and test caregiver self-management interventions that are low-tech, easily accessible and linguistically and culturally appropriate to improve the abilities of Latino caregivers of persons with Early Onset Dementia (EOD) and minimize negative outcomes and maximize healthy behaviors and quality of life. Study will enroll 60 caregivers from 15-20 Latino families with a family member diagnosed with EOD. Participants will be randomly assigned by family, based on the person with EOD and the severity/length of their illness.
Investigator:
Freddi Segal-Gidan, PA, PhD
Sponsor:
Funding:
Indication:
Diabetic foot ulcer
Title:
Assistive ExoSkeleton and ExoTendon System for Increased Return of Limb Function after Diabetic Foot Ulcer
Description:
This study would like to assess the comfort and acceptance of shoes with an exoskeleton (FlyBand) device in people who have had diabetic foot ulcers (DFUs) compared to regular diabetic footwear.
Investigator:
David Armstrong, DPM
Sponsor:
Funding:
Indication:
Diabetic foot ulcer
Title:
Improving the science of adherence reinforcement and safe mobility in people with diabetic foot ulcers using smart offloading
Description:
Comparative randomized trial that will follow 201 adult patients with diabetic foot ulcer and randomized to one of 3 groups: Group 1: REFERENCE GROUP: MOTUS boot rendered irremovable with cohesive bandage; no feedback on adherence; Group 2: CONTROL GROUP: MOTUS boot, removable, without feedback on adherence; Group 3: INTERVENTION GROUP: MOTUS boot removable, with reinforcement of adherence via smartwatch and smartphone as well as remote patient monitoring. Subjects will be followed weekly for 12 weeks and follow-up phone call at 52 weeks.
Investigator:
David Armstrong, DPM
Sponsor:
Funding:
Indication:
Diabetic foot ulcer
Title:
Insight into the Sole: Using Infrared Eyes (iREyes) to assess diabetic foot ulcer healing and recurrence
Description:
Prospective, blinded study of the iREyes device to see if it can track diabetic foot ulcer healing and predict future recurrence. The device was developed by Eden Medical and uses infrared imaging as well as a visual camera. There are 2 phases and the results of the imaging will not be known until after the study is completed.
Investigator:
David Armstrong, DPM
Sponsor:
Funding:
Indication:
Epilepsy
Title:
REALIZE
Description:
A Randomized, Double-blind, Placebo-controlled, Parallel group, Multicenter Trial of CVL-865 as Adjunctive Therapy in Adults with Drug-Resistant Focal Onset Seizures
Investigator:
Hui Gong, MD
Sponsor:
Cereval Therapeutics, LLC
Funding:
Industry
Indication:
Epilepsy
Title:
Illuminate
Description:
A Phase 4, Long-Term Safety Study to Assess the Potential for Chronic Liver Injury in Participants Treated with Epidiolex (Cannabidiol) Oral Solution
Investigator:
Hui Gong, MD
Sponsor:
GW Research LTD
Funding:
Industry
Indication:
Epilepsy
Title:
STARZ - Blinded
Description:
A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Outpatient, Parallel-Group Study to Assess the Efficacy and Safety of Staccato Alprazolam in Participants 12 years of Age and Older with Stereotypical Prolonged Seizures (EP0162)
Investigator:
Hui Gong, MD
Sponsor:
UCB Biopharma SRL
Funding:
Industry
Indication:
Epilepsy
Title:
PACIFIC
Description:
A Phase 1b/2a randomized, double-blind, placebo-controlled, parallel-group, dose-escalation study to investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, and exploratory efficacy of LP352 in subjects with developmental and epileptic encephalopathies
Investigator:
Susan Shaw, MD
Sponsor:
Longboard Pharmaceuticals
Funding:
Industry
Indication:
Epilepsy
Title:
Model-based neural control of brain stimulation for neuropsychiatric disorders
Description:
Proof-of-concept, NIH-funded study that would like to understand how mental states are represented in brain signals and help develop new brain stimulation treatments in patients that have severe mental disorders, such as major depression, for whom no existing treatment is effective. Study subjects will be epilepsy patients aged 18 and older undergoing intracranial electroencephalography (iEEG) as part of standard care. Research procedures include completion of mood assessments and food desirability and extended direct intracranial stimulation, initially for up to one hour, and possibly a second time to correlate data.
Investigator:
Naryam Shanechi, MD
Sponsor:
Funding: